Melatonina
Anno: 1999
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Riferimento:Environ Health Perspect. 1999 Feb;107 Suppl 1:145-54. Review.Azione della melatonina:Melatonin-breast cancer and EMF-breast cancer hypotheses.Target:Electromagnetic fields (EMF).
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Riferimento:Immunology. 1999 Feb;96(2):291-7.Azione della melatonina:Dhea and Mlt simultaneously reduced hepatic lipid peroxidation and prevent vitamin E loss.Target:Prevent (Th1, Th2) cyto-kine dysregulation.
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Riferimento:FASEB J. 1999 May;13(8):857-68.Azione della melatonina:Melatonin interferes with the activation of estrogen receptor by estradiol.Target:Estrogen receptor DNA.
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Riferimento:J Pineal Res. 1999 Jan;26(1):1-8.Azione della melatonina:Melatonin may have a role in the regulation of peripheral blood cell counts.Target:Serum melatonin/circadian rhythms.
Anno: 2000
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Riferimento:J Pineal Res. 2000 May;28(4):210-8.Azione della melatonina:The growth-inhibitory effects of melatonin are transduced through the membrane-associated G-protein coupled mt1 melatonin receptor.Target:Estrogen receptor (ER).
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Titolo: Melatonin and climacteryRiferimento:Med Sci Monit. 2000 Nov-Dec;6(6):1209-12. Review.Azione della melatonina:Melatonin has the potential to markedly delay the appearance of palpable mammary tumors, combination with flaxseed oil caused a significant decrease in the number/weight of tumors.Target:Delay/prevent breast cancer.
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Riferimento:Pathophysiology. 2000 Apr;7(1):47-51.Azione della melatonina:Essential participation of endogenous opioids in hormonal regulation, a response to stress caused by beginning chemotherapy.Target:Stress in the course of neoplastic diseases.
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Titolo: Melatonin, experimental basis for a possible application in breast cancer prevention and treatmentRiferimento:Histol Histopathol. 2000 Apr;15(2):637-47. Review.Azione della melatonina:Melatonin (1nM) actions support a possible usefulness in the prevention and treatment of mammary gland malignancy.Target:Inhibit in vitro proliferation of MCF-7.
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Riferimento:J Natl Cancer Inst. 2000 May 3;92(9):686-9.Azione della melatonina:Melatonin may act as an antioxidant that can scavenge free radicals and protect against DNA damage.Target:Reduce chemotherapy toxicity.
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Riferimento:Br J Cancer. 2001 Feb 2;84(3):397-9.Azione della melatonina:Our findings give support to the 'melatonin hypothesis'.Target:Visually impaired women.