Melatonina
Anno: 2006
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Titolo: Antiestrogens modulate MT1 melatonin receptor expression in breast and ovariancancer cell linesRiferimento:Oncol Rep. 2006 Jan;15(1):231-5.Azione della melatonina:Data suggest that melatonin signaling is modulated by antiestrogens in breast and ovarian cancer cells.Target:MT1 melatonin receptor.
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Riferimento:Int J Biol Markers. 2006 Oct-Dec;21(4):242-5.Azione della melatonina:Our data suggest that storage temperatures might affect degradation of aMT6s during storage.Target:6-sulfatoxymelatonin (aMT6s).
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Riferimento:Cancer Detect Prev. 2006;30(2):118-28.Azione della melatonina:Melatonin oncostatic actions on hormone-dependent mammary tumors are mainly based on its antiestrogenic actions, also by regulating the activity of the aromatases.Target:Estrogen-signaling pathways.
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Riferimento:J Pineal Res. 2006 Mar;40(2):116-24.Azione della melatonina:Age, reproductive and menopausal factors, body mass index (BMI), alcohol consumption, smoking history, night shift work were significantly related to lower levels of melatonin, whereas parity was significantly associated with higher aMT6s levels.Target:6-sulfatoxymelatonin (aMT6s)
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Riferimento:Epidemiology. 2006 Jan;17(1):108-11.Azione della melatonina:Results suggest a modestly elevated risk of breast cancer after longer periods of rotating night work.Target:Shift work.
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Riferimento:Vopr Onkol. 2006;52(5):491-8.Azione della melatonina:No abstract available.Target:No abstract available.
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Riferimento:J Am Assoc Lab Anim Sci. 2006 May;45(3):38-44.Azione della melatonina:Melatonin (MLT), eicosapentaenoic acid (EPA), and conjugated linoleic acid (CLA) inhibit growth and metabolism in several rodent and human tumors, to suppress tumor uptake of linoleic acid (LA).Target:MLT, EPA, CLA, LA.
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Riferimento:Indian J Med Sci. 2006 Dec;60(12):523-35.Azione della melatonina:Exposure to light at night (LAN) and anthropogenic electric and magnetic fields (EMFs) is related to the increased incidence of breast cancer and childhood leukaemia via melatonin disruption.Target:Immunomodulator and oncostatic agent.
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Riferimento:J Pineal Res. 2006 May;40(4):291-6.Azione della melatonina:In vivo, Cd mimics the effect of estrogens in the uterus and mammary gland. Melatonin is a specific inhibitor of Cd-induced ER alpha-mediated transcription.Target:ER alpha and ER beta.
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Riferimento:Int J Exp Pathol. 2006 Apr;87(2):81-7.Azione della melatonina:Powerful antiapoptotic signal promoting the survival of normal granulocytes and B lymphocytes.Target:T-helper 1 (Th1) cytoki- nes, natural killer (NK) cells.