Melatonina
Anno: 2006
-
Riferimento:J Pineal Res. 2009 Jan;46(1):15-21Azione della melatonina:Melatonin(1nM) inhibits cancer cell invasion and metastasis formation via ROCK-regulated microfilament and microtubule organization,through increased expression of two cell surface adhesion proteins, E-cadherin and beta(1)-integrin.Target:Rho-associated proteinkinase (ROCK).
-
Titolo: Risk of breast cancer after night- and shift work: current evidence and ongoing studies in DenmarkRiferimento:Cancer Causes Control 2006 May;17(4):531-7.
-
Riferimento:J Sleep Res. 2006 Sep;15(3):241-9.Azione della melatonina:Little evidence that sleeping few hours per night was associated with breast cancer risk.Target:Circadian rhythms by melatonin.
-
Titolo: Light during darkness and cancer: relationships in circadian photoreception and tumor biologyRiferimento:Cancer Causes Control. 2006 May;17(4):515-23.Azione della melatonina:The circadian rhythm for pineal melatonin secretion is regulated by the hypothalamic suprachiasmatic nucleus (SCN).Action spectra of melatonin suppression by light have shown that light in the 446-477 nm range,higher risk of breast cancer in industrialized countries is partly due to increased exposure to light at night.Target:LAN
-
Riferimento:Cancer Causes Control. 2006 May;17(4):501-7.Azione della melatonina:Circadian disruption could lead to alterations in melatonin production and can increase breast tumorigenesis in experimental animals. Exogenous administration of melatonin has been shown to phase shift humans depending on the time of day it's given.Target:Circadian clock in the suprachiasmatic nuclei.
-
Riferimento:J Carcinog. 2006 Aug 10;5:20.Azione della melatonina:Light plays on nocturnal melatonin production and the incidence of breast cancer.Target:LAN
-
Riferimento:Cancer Causes Control. 2006 May;17(4):375-83.Azione della melatonina:Nocturnal rodents are frequently used as models in C human breast cancer research, the circadian systems of nocturnal rodents are approximately 10,000 times moresensitive toopticalradiation than that ofhumans.Target:Circadian disruption and breast cancer.
-
Titolo: Biomarkers, fatigue, sleep, and depressive symptoms in women with breast cancer: a pilot studyRiferimento:Oncol Nurs Forum. 2006 Jul 1;33(4):775-83.Azione della melatonina:Fatigue, sleep, and depressive symptoms are more prevalent in women with cancer than a cancer-free comparison group.Target:Wrist, Sleep, Actigraphy.
-
Riferimento:Cancer Res. 2006 Apr 1;66(7):3954; author reply 3954.Azione della melatonina:No abstract available.Target:No abstract available.
-
Riferimento:Neuro Endocrinol Lett. 2006 Jun;27(3):351-4.Azione della melatonina:The effects of MLT and CGP 52 608 (the selective ligand for nuclear RZR/ROR receptors) were comparable with suppression caused by methotrexate.Target:CGP 52608