Melatonina
Anno: 2008
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Riferimento:G Ital Med Lav Ergon. 2008 Jul-Sep;30(3):276-9.Azione della melatonina:Shift-work has been associated with breast cancer, due to a circadian disruption and to a nocturnal suppression in melatonin production.Target:Shift-work.
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Riferimento:Endokrynol Pol. 2008 May-Jun;59(3):200-6.Azione della melatonina:Not influenced the activity of GSH-Px, either in normal or in pinealectomised rats after ADR. A deficiency of endogenous melatonin production may inhibit GSH-Px activity.Target:ADR; GSH-Px.
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Titolo: Melatonin and estradiol effects on food intake, body weight, and leptin in ovariectomized ratsRiferimento:Maturitas. 2007 Sep 20;58(1):91-101.Azione della melatonina:In ovariectomized rats,melatonin reduced food intake and partially prevented the increase of body weight and cholesterol, without changing leptin levels.Target:Sulphatoxymelatonin (aMT6s).
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Riferimento:J Pineal Res. 2008 Apr;44(3):307-15.Azione della melatonina:Melatonin administration (2 mg/kg BW/day) enhances survival under LD conditions, the results are self-defeating when they coexist with circadian disruption as under LL conditions.Target:Light-dark (LD) Continuous light (LL).
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Riferimento:Br J Cancer. 2008 Nov 4;99(9):1502-5.Azione della melatonina:In a prospective study on Japanese women, short sleep duration was associated with higher risk of breast cancer.Target:LAN
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Riferimento:Hybridoma (Larchmt). 2008 Jun;27(3):205-9.Azione della melatonina:Anti-melatonin monoclonal antibodies (Mab) may be useful for immunoassay of melatonin.Target:Mab-BSA( bovine serum albumin) intraperitonally.
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Riferimento:J Pineal Res. 2008 Apr;44(3):307-15.Azione della melatonina:Importance of taking into account endogenous rhythmicity and limiting melatonin administration to the subjective night (2 mg/kg BW/day) in order to restrict melanoma progression.Target:Circadian rhythmicity.
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Riferimento:Breast Cancer Res Treat. 2008 Apr;108(3):339-50.Azione della melatonina:Melatonin,at physiological concentration,suppresses estrogen receptor(ER) gene, modulates several estrogen dependent regulatory proteins and pro-oncogenes, inhibits cell proliferation, and impairs the metastatic capacity of MCF-7 human breast cancer cells.Target:Estrogen receptor (ER)
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Riferimento:In Vivo. 2008 May-Jun;22(3):397-400.Azione della melatonina:MLT with s.c. low-dose IL-2 caused a statistically significant reduction of the radiotherapy-induced effect.Target:Lymphocyte growth factor (IL-2).
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Riferimento:Integr Cancer Ther. 2008 Sep;7(3):189-203.Azione della melatonina:Melatonin's oncostatic actions include the direct augmentation of natural killer (NK) cell activity, which increases immunosurveillance, stimulation of cytokine production and protection on hematopoietic precursors from the toxic effect of anticancer chemotherapeutic drugs.Target:Immunomodulation, hematopoiesis, and antioxidative processes.