Melatonina
Anno: 2012
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Riferimento:Eur J Pharmacol. 2012 Apr 15;681(1-3):34-43.Azione della melatonina:Administration of melatonin with all-trans retinoic acid and somatostatin may be of significant therapeutic benefit in breast cancer.Target:Melatonin effects potentiated
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Riferimento:Eur J Cancer Prev. 2012 Mar;21(2):163-70.Azione della melatonina:Resveratrol in combination with melatonin has some protective effects on N-methyl-N-nitrosourea (NMU)-induced rodent breast cancer.Target:Chemoprevention with resveratrol and mlt.
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Riferimento:Int J Cancer. 2012 May 30.Azione della melatonina:Sleep duration is not significantly associated with breast cancer risk reduction.Target:6-sulfatoxymelatonin (aMT6s)
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Riferimento:Breast Cancer Res Treat. 2012 Apr;132(2):693-9.Azione della melatonina:Genetic variation in the MTNR1a and 1b genes may contribute to breast cancer, no breast cancer associations were found for variants in the AANAT gene.Target:Mlt receptors 1a and 1b (MTNR1a and MTNR1b), arylalkylamine N-acetyl-transferase (AANAT).
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Riferimento:Dig Dis Sci. 2012 Oct 10.Azione della melatonina:Supplementation by exogenous melatonin (20 and 40 mg/kg body weight) significantly reduces MTX-induced small intestinal damage.Target:Methotrexate (MTX).
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Riferimento:Oncol Rep. 2012 Aug;28(2):418-28.Azione della melatonina:Circadian system alteration and melatonin reduction, for exposure to light-at-night during night shift work, is the most valid hypotheses on the relation of shift work and breast cancer.Target:Night shift work
Anno: 2013
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Riferimento:Breast Cancer Res Treat. 2013 Feb;137(3):677-87.Azione della melatonina:Melatonin or a melatonin receptor agonist may be useful biologic additions in the treatment of some forms of triple negative human breast carcinoma.Target:TNBC
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Riferimento:BMC Cell Biol. 2013 Jan 7;14:1.Azione della melatonina:Melatonin enhance DNA repair capacity by affecting several key genes involved in DNA damage responsive pathways.Target:DNA repair capacity