Neoplasie della mammella
Anno: 2000
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Riferimento:J Pineal Res. 2000 Jan;28(1):41-7.Azione della melatonina:The inclusion of morning urine widespread testing of the role played by melatonin in human health and disease.Target:6-hydroxymelatonin-sulfate (6-OHMS).
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Riferimento:Life Sci. 2000 Nov 3;67(24):2953-60.Azione della melatonina:Melatonin (10(-8)-10(-10) M) may be an inhibitor of human mammary and ovarian carcinoma.Target:Pineal substances shown tumor inhibiting activity.
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Titolo: Influence of radiotherapy on 6-sulphatoxymelatonin levels in the urine of brain cancer patients.Riferimento:Neuro Endocrinol Lett. 2000;21(3):203-207.Azione della melatonina:Wide variation in the mean concentration of aMT6S excreted in the urine.Target:6-sulphatoxymelatonin
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Titolo: Growth-inhibitory activity of melatonin on human androgen-independent DU 145 prostate cancer cellsRiferimento:Prostate. 2000 Nov 1;45(3):238-44.Azione della melatonina:Melatonin exerts a direct oncostatic activity on human androgen-independent prostate cancer cells, and on breast cancer.Target:Mel nuclear receptors.
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Riferimento:Epidemiology. 2000 Nov;11(6):660-5.Azione della melatonina:Alcoholic beverages may suppress circulating melatonin levels, and an incrising circulating estrogen could increase the risk of breast cancer.Target:6-sulfatoxymelatonin
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Titolo: Melatonin effects on intercellular junctional communication in MCF-7 human breast cancer cellsRiferimento:J Pineal Res. 2000 Oct;29(3):166-71.Azione della melatonina:Melatonin (10 microM) could exert its antitumor action by increasing regulatory signals that are passed between adjacent epithelial cells through intercellular junctions.Target:Gap junctional intercellular communication.
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Riferimento:Environ Health Perspect. 2000 Sep;108(9):797-802.Azione della melatonina:These differences include the use of different substrains of Sprague-Dawley rats and differences in MFexposure metrics.Target:50-Hz magnetic field (MF)
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Riferimento:Wiad Lek. 2000;53(5-6):283-8.Azione della melatonina:CMF did not influence the interactions between GH and other (melatonin) studied parameters.Target:Cyclophosphamide, Me-thotrexate, 5-Fluorouracil (CMF).
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Titolo: The modulation of oestrogen receptor-alpha activity by melatonin in MCF-7 human breast cancer cellsRiferimento:Eur J Cancer. 2000 Sep;36 Suppl 4:117-8.Azione della melatonina:No abstract available.Target:No abstract available.
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Riferimento:Breast Cancer Res Treat. 2000 Jun;61(3):229-39.Azione della melatonina:Sequential treatment of Mlt and atRA may induceapoptosis by modulation of members of the death suppressor (Bcl-2) family of proteins.Target:Death suppressor (Bcl-2).