Neoplasie della mammella
Anno: 2002
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Riferimento:Chronobiol Int. 2002 Jan;19(1):221-35.Azione della melatonina:The relationships between melatonin biology and breast cancer require exploration.Target:Circadian rhythms.
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Riferimento:J Emerg Nurs. 2002 Apr;28(2):169-71.Azione della melatonina:No abstract available.Target:No abstract available.
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Titolo: Melatonin deficiencies in womenRiferimento:Maturitas. 2002 Apr 15;41 Suppl 1:S85-104.Azione della melatonina:In Nordic countries indigenous people suffer less from breast and prostate cancer, winter darkness seems to protect.Target:Melatonin hypothesis
Anno: 2003
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Riferimento:Neuro Endocrinol Lett. 2003 Dec;24(6):440-4.Azione della melatonina:The growth of all ERalpha-positive breast cancer cell lines can be inhibited by melatonin (10(-9)M).Target:Estrogen receptors
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Riferimento:Epidemiology. 2003 Sep;14(5):514-20.Azione della melatonina:The results of this large investigation are consistent with those of most previous studies, and do not support the hypothesis that electric blanket use is associated with increased breast cancer risk.Target:EMF
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Riferimento:Breast Cancer Res Treat. 2003 Jun;79(3):313-20.Azione della melatonina:The first biological evidence for a potential link between constant light exposure and increased human breast oncogenesis involving MLT suppression and stimulation of tumor linoleic acid (LA)metabolism.Target:LAN/Linoleic Acid(LA)
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Riferimento:Crit Rev Oncol Hematol. 2003 Jun;46(3):221-34.Azione della melatonina:Pineal peptide preparation Epithalamin and synthetic tetrapeptide Epitalon (Ala-Glu-Asp-Gly) are potent inhibitors of mammary carcinogenesis in ro-dents and might be useful in the prevention of breast cancer in women at risk.Target:LAN
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Riferimento:Endocr Relat Cancer. 2003 Jun;10(2):153-9.Azione della melatonina:Melatonin (1 nM) down-regulates the expression of estrogen receptor (ERalpha) and inhibits the binding of the estradiol-ER complex to the estrogen response element (ERE) in the DNA.Target:Eralpha/ERE
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Riferimento:J Surg Res. 2003 Apr;110(2):332-7.Azione della melatonina:Combination therapy with 1,25-(OH)(2)-D(3) and MEL in the treatment of breast cancer suggest that the growth inhibition could be related to the enhanced TGF-beta(1) secretion.Target:Dihydroxyvitamin D(3) Transforming growth-factor beta 1
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Riferimento:J Natl Cancer Inst. 2003 Jun 4;95(11):825-8.Azione della melatonina:These data suggest that working a rotating night - shift at least three nights per month for 15 or more years may increase the risk of colorectal cancer in women.Target:LAN