Riferimento:
Eksp Klin Farmakol. 2011;74(9):23-7.
Autori:
Grinin MG, Shimanovskiĭ NL.
Fonte:
Eksp Klin Farmakol. 2011;74(9):23-7.
Anno:
2011
Azione:
(111)In-octreotide per la diagnostica di neoplasie con elevata espressione dei recettori della somatostatina.
Target:
(111)In-octreotide/neoplasie con elevata espressione dei recettori della somatostatina.
ABSTRACT
We have studied the possibility of using octreoitid labeled by indium-111 for radionuclide diagnostics of neoplasms with high expression of somatostatin receptors. It has been established that, using experiments with cell cultures, it is possible to predict the application of 111In-labeled octreotid and determine time intervals for the best visualization of tumors. Indium-111-labeled octreotid accumulation in animals with transferred B16 tumor (pigment melanoma) shows evidence for the opportunity of using this substance as radiopharmaceutical medium for tumor diagnostics.
Sostanze: