ABSTRACT
Giant condyloma acuminatum (GCA), or Buschke-Löwenstein tumour (BLT), is a rare large tumour of the anogenital area. It is caused by human papillomavirus genotypes 6 and 11, and it is characterized by aggressive local invasion and frequent recurrences after treatment. Treatment of choice is radical excision, although chemotherapy and radiation are also used in special cases. We report a case of a young man with anogenital GCA, presenting with a large perianal mass and pain during defaecation. The patient was treated by surgical removal of almost the entirety of the mass, using radiofrequency surgical dissection. The concurrent use of oral acitretin for the treatment of erythrodermic psoriasis led to elimination of the remaining disease. The patient remains free of disease 26 months after the end of treatment.
Therapeutic combination of radiofrequency surgical dissection and oral acitretin in the management of perianal Buschke-Lowenstein tumour: a case report
Riferimento:
Int J STD AIDS. 2012 May;23(5):362-4.
Autori:
Mavrogianni P, Fallidas E, Nicolaidou E, Villias K, Stefanaki I, Katsambas A, Lira T, Apostolopoulos P, Androne I, Rouvas G, Tsibouris P, Alexandrakis G. titi_mav@yahoo.gr
Fonte:
Int J STD AIDS. 2012 May;23(5):362-4.
Anno:
2012
Azione:
Rimozione chirurgica e l'uso concomitante di acitretina orale (attivatore del recettore nucleare dell'acido retinoico) nel il trattamento della psoriasi eritrodermica ha portato alla eliminazione della malattia residua.
Target:
Acitretina/psoriasi eritrodermica.
Sostanze: