Neoplasie della mammella

Anno: 1990

Titolo: Pineal gland and tumor cell kinetics: serum levels of melatonin in relation to Ki-67 labeling rate in breast cancer

Riferimento:
Oncology. 1990;47(3):275-7.

Azione della melatonina:
Breast cancer patients showed significantly higher mean values of melatonin than controls.

Target:
Antineoplastic role
Titolo: Non parametric testing of melatonin characteristics as potential markers of breast cancer risk

Riferimento:
Prog Clin Biol Res. 1990;341A:21-30.

Azione della melatonina:
The re-evaluation of ML data by BS provides statistical validation of a test battery for breast cancer risk.

Target:
Bubble Sort (BS)
Titolo: Plasma melatonin in patients with breast cancer

Riferimento:
Oncology. 1990;47(5):401-5.

Azione della melatonina:
Multiple-regression tests showed a inverse correlation between survival and melatonin values.

Target:
Daytime plasma melatonin values
Titolo: Oncostatic effects of the pineal gland

Riferimento:
Drug Metabol Drug Interact. 1990;8(3-4):313-9. Review.

Azione della melatonina:
Melatonin receptors are the sites of interaction between melatonin and the tumor cell.

Target:
Melatonin receptor

Anno: 1991

Titolo: Effects of melatonin on the cell cycle kinetics and "estrogen-rescue" of MCF-7 human breast cancer cells in culture

Riferimento:
J Pineal Res. 1991 Jan;10(1):36-42.

Azione della melatonina:
Antiproliferative effect of melatonin is cell cycle specific by causing a G1-S transition delay.

Target:
G1 phase/S phase
Titolo: [Role of the pineal body in reproduction and in gynecologic tumors]

Riferimento:
Geburtshilfe Frauenheilkd. 1991 Jan;51(1):1-8. Review.

Azione della melatonina:
Serum melatonin is depressed in patients with primary mammary cancer.

Target:
Mlt/ menopause
Titolo: Use of electric blankets and risk of postmenopausal breast cancer

Riferimento:
Am J Epidemiol. 1991 Jul 15;134(2):180-5.

Azione della melatonina:
Chronic exposure to 60-Hz electromagnetic fields has increased breast cancer risk by suppressing the normal nocturnal rise in melatonin.

Target:
Electric blankets
Titolo: Seasonal changes in serum melatonin in women with previous breast cancer

Riferimento:
Br J Cancer. 1991 Jul;64(1):149-53.

Azione della melatonina:
The abnormal reduction of serum melatonin seen in winter time could promote tumour growth of breast cancer at this season.

Target:
Seasonal variation
Titolo: Depression of serum melatonin in patients with primary breast cancer is not due to an increased peripheral metabolism

Riferimento:
Cancer. 1991 Mar 15;67(6):1681-4.

Azione della melatonina:
The depression of circulating melatonin in patients with primary breast cancer must be due to a reduced activity of the pineal gland.

Target:
6-sulfatoxymelatonin

Anno: 1992

Titolo: Melatonin augments the sensitivity of MCF-7 human breast cancer cells to tamoxifen in vitro

Riferimento:
J Clin Endocrinol Metab. 1992 Aug;75(2):669-70.

Azione della melatonina:
Melatonin (232 ng/mL) augments the inhibitory actions of tamoxifen.

Target:
MLT/ Tamoxifene

A.I.A.N. - Modena

Anno: 1990

Anno: 1991

Anno: 1992

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