Neoplasie della mammella

Target

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Azione della melatonina

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Anno: 1993

Titolo: Breast cancer and electric power

Riferimento:
Biomed Pharmacother. 1993;47(10):435-8. Review.

Azione della melatonina:
These can reduce nocturnal melatonin production.

Target:
Light-at-night/electromagnetic fields
Titolo: Electromagnetic fields and male breast cancer

Riferimento:
Biomed Pharmacother. 1993;47(10):425-7. Review

Azione della melatonina:
Pineal function is suppressed by light-at-night(LAN) 60-Hz electric fields suppress the nocturnal rise in pineal melatonin production.

Target:
Electromagnetic fields Light-at-night

Anno: 1994

Titolo: Diminished pineal function coincides with disturbed circadian endocrine rhythmicity in untreated primary cancer patients. Consequence of premature aging or of tumor growth?

Riferimento:
Ann N Y Acad Sci. 1994 May 31;719:502-25. Review.

Azione della melatonina:
No abstract available.

Target:
No abstract available.
Titolo: 5-Fluorouracil attenuates an oncostatic effect of melatonin on estrogen-sensitive human breast cancer cells (MCF7)

Riferimento:
Cancer Lett. 1994 Jun 15;81(1):95-8.

Azione della melatonina:
Melatonin(0,3nM)inhibited MCF7 cell growth, effect of melatonin was reduced by the co-administration of 5-FU.

Target:
5-fluorouracil (5-FU)
Titolo: Effects of weak alternating magnetic fields on nocturnal melatonin production and mammary carcinogenesis in rats

Riferimento:
Oncology. 1994 May-Jun;51(3):288-95.

Azione della melatonina:
Nocturnal melatonin levels were significantly reduced by exposure to this weak alternating MF.

Target:
Magnetic fields (MFs)
Titolo: Interaction between melatonin and estradiol on morphological and morphometric features of MCF-7 human breast cancer cells

Riferimento:
J Pineal Res. 1994 May;16(4):215-22.

Azione della melatonina:
Antitumor effect through a cell-cycle-specific mechanism by delaying the entry of cells into mitosis.

Target:
Smaller cell and nuclear sizes
Titolo: Animal studies on the role of 50/60-Hertz magnetic fields in carcinogenesis

Riferimento:
Life Sci. 1994;54(21):1531-43. Review.

Azione della melatonina:
Reduction of circulating levels of melatonin.

Target:
50/60-Hz MF
Titolo: Modulation of estrogen receptor mRNA expression by melatonin in MCF-7 human breast cancer cells.

Riferimento:
Mol Endocrinol. 1994 Dec;8(12):1681-90.

Azione della melatonina:
Antiproliferative actions of Mlt are mediated through the suppression of the transcription of ER gene.

Target:
Estrogen receptor (ER) mRNA
Titolo: Serial transplants of 7,12-dimethylbenz[a]anthracene-induced mammary tumors in Fischer rats as model system for human breast cancer. 3. Quantitative ultrastructural studies of the pinealocytes and plasma melatonin concentrations in rats bearing an advance

Riferimento:
Biol Signals. 1994 Nov-Dec;3(6):302-6.

Azione della melatonina:
Plasma melatonin concentrations in tumor-bearing rats killed at 3.00 h were suppressed by 35% when compared to the control animals killed at the same time.

Target:
Plasma melatonin concentrations
Titolo: Differences between pulsatile or continuous exposure to melatonin on MCF-7 human breast cancer cell proliferation

Riferimento:
Cancer Lett. 1994 Sep 30;85(1):105-9.

Azione della melatonina:
Antiproliferative effect was obtained by sequential exposure to 10(-9) M/10(-11)M 12/12h melatonin, which mimics the physiological rhythm of serum melatonin concentration.

Target:
Physiological rhythm/serum melatonin concentration

A.I.A.N. - Modena

Neoplasie della mammella

Anno: 1993

Anno: 1994

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