Neoplasie della mammella

Target

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Azione della melatonina

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Anno: 1995

Titolo: Hypotheses: melatonin/steroid combination contraceptives will prevent breast cancer

Riferimento:
Breast Cancer Res Treat. 1995 Mar;33(3):257-64.

Azione della melatonina:
Melatonin/ovarian-steroid contraceptive will restore the lost mechanism of endogenous anovulation.

Target:
Seasonal ovulation
Titolo: Melatonin modulation of estrogen-regulated proteins, growth factors, and proto-oncogenes in human breast cancer

Riferimento:
J Pineal Res. 1995 Mar;18(2):93-103.

Azione della melatonina:
Melatonin (10(-9) M) induces growth inhibition in breast tumor cells.

Target:
Estrogen receptor (ER)
Titolo: Meditation, melatonin and breast/prostate cancer: hypothesis and preliminary data

Riferimento:
Med Hypotheses. 1995 Jan;44(1):39-46.

Azione della melatonina:
Mindfulness meditation is associated with increased physiological levels of melatonin.

Target:
Effect of meditation on 6-sulphatoxymelatonin

Anno: 1996

Titolo: A phase II study of tamoxifen plus melatonin in metastatic solid tumour patients

Riferimento:
Br J Cancer. 1996 Nov;74(9):1466-8.

Azione della melatonina:
Combination with Tamoxifene plus Melatonin (20 mg day) may have some benefit in untreatable metastatic solid tumour patients.

Target:
Melatonin/tamoxifen
Titolo: Melatonin in human breast cancer tissue: association with nuclear grade and estrogen receptor status

Riferimento:
Lab Invest. 1996 Oct;75(4):557-61.

Azione della melatonina:
ExogenousMLT may influence nuclear grade and/or estrogen receptor activity in breast cancer patients.

Target:
Nuclear grade/melatonin
Titolo: "The enzymatic basis for the rat liver 6-hydroxymelatonin sulfotransferase activity"

Riferimento:
J Pineal Res. 1996 Apr;20(3):173.

Azione della melatonina:
No abstract available.

Target:
No abstract available.
Titolo: Study on pineal function and DMBA-induced breast cancer formation in rats during exposure to a 100-mG, 50 Hz magnetic field

Riferimento:
J Toxicol Environ Health. 1996 Jun 7;48(2):169-85.

Azione della melatonina:
50-Hz, 100-mG MF significantly decreases circulating melatonin but is not associated with a development of DMBA-induced mammary tumors.

Target:
Dimethylbenzanthracene (DMBA) Magnetic field (MF)
Titolo: Melatonin inhibits DNA synthesis in MCF-7 human breast cancer cells in vitro

Riferimento:
Life Sci. 1996 May 24;58(26):2447-53.

Azione della melatonina:
Melatonin (1nM) antiproliferative effects could be mediated by a reduction of DNA synthesis.

Target:
Mitotic block in S phase
Titolo: Exposure of DMBA-treated female rats in a 50-Hz, 50 microTesla magnetic field: effects on mammary tumor growth, melatonin levels, and T lymphocyte activation.

Riferimento:
Carcinogenesis. 1996 May;17(5):903-10.

Azione della melatonina:
Nocturnal serum melatonin determination at 50 microT did not yield significant differences.

Target:
Magnetic fields (MF) Dimethylbenzanthracene (DMBA)
Titolo: Incidence of breast cancer in Norwegian female radio and telegraph operators

Riferimento:
Cancer Causes Control. 1996 Mar;7(2):197-204.

Azione della melatonina:
Results support an association between work as a radio and telegraph operator and breast cancer for disturbances of chronobiological parameters.

Target:
Decrement of melatonin

A.I.A.N. - Modena

Neoplasie della mammella

Anno: 1995

Anno: 1996

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