Neoplasie della mammella
Anno: 2000
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Titolo: Melatonin and climacteryRiferimento:Med Sci Monit. 2000 Nov-Dec;6(6):1209-12. Review.Azione della melatonina:Melatonin has the potential to markedly delay the appearance of palpable mammary tumors, combination with flaxseed oil caused a significant decrease in the number/weight of tumors.Target:Delay/prevent breast cancer.
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Riferimento:Front Neuroendocrinol. 2000 Apr;21(2):133-70. Review.Azione della melatonina:The small number of clinical studies focusing on the possible therapeutic value of melatonin (1nM) on breast cancer is surprising.Target:Melatonin's antitumoral actions.
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Riferimento:Ann Epidemiol. 2000 Jan;10(1):31-44. Review.Azione della melatonina:EMF and light at night, might contribute to mammary carcinogenesis through inhibition of melatonin.Target:Electromagnetic fields (EMF).
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Riferimento:Br J Cancer. 2001 Feb 2;84(3):397-9.Azione della melatonina:Our findings give support to the 'melatonin hypothesis'.Target:Visually impaired women.
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Riferimento:Life Sci. 2000 Nov 3;67(24):2953-60.Azione della melatonina:Melatonin (10(-8)-10(-10) M) may be an inhibitor of human mammary and ovarian carcinoma.Target:Pineal substances shown tumor inhibiting activity.
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Riferimento:J Pineal Res. 2000 Jan;28(1):41-7.Azione della melatonina:The inclusion of morning urine widespread testing of the role played by melatonin in human health and disease.Target:6-hydroxymelatonin-sulfate (6-OHMS).
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Titolo: Growth-inhibitory activity of melatonin on human androgen-independent DU 145 prostate cancer cellsRiferimento:Prostate. 2000 Nov 1;45(3):238-44.Azione della melatonina:Melatonin exerts a direct oncostatic activity on human androgen-independent prostate cancer cells, and on breast cancer.Target:Mel nuclear receptors.
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Titolo: Influence of radiotherapy on 6-sulphatoxymelatonin levels in the urine of brain cancer patients.Riferimento:Neuro Endocrinol Lett. 2000;21(3):203-207.Azione della melatonina:Wide variation in the mean concentration of aMT6S excreted in the urine.Target:6-sulphatoxymelatonin
Anno: 2001
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Riferimento:Cancer Causes Control. 2001 Apr;12(3):279-87. Review.Azione della melatonina:Electric lighting contributes to 'circadian disruption' may be an important cause of 'endocrine disruption' and contribute to a high risk of breast cancer.Target:LAN
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Riferimento:Carcinogenesis. 2001 Jul;22(7):1043-8.Azione della melatonina:MF may cause uncoupling of signal transduction from melatonin receptors to adenylyl cyclase.Target:Magnetic fields/cAMP