Neoplasie della mammella
Anno: 2001
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Riferimento:Bioelectromagnetics. 2001 Feb;22(2):122-8.Azione della melatonina:Melatonin inhibits the growth of mammary tumors in animals. No changes have been found in melatonin levels in climaterical women.Target:Endometrial cancer and Alzheimer's disease.
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Riferimento:Am J Epidemiol. 2001 Oct 1;154(7):591-600.Azione della melatonina:Exposure to night-time residential 60-Hz magnetic fields can depress the normal nocturnal rise in melatonin.Target:6-sulfatoxymelatonin
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Riferimento:Environ Res. 2001 Feb;85(2):115-21.Azione della melatonina:Long-term and continuous exposure to simulate powerline magnetic fields did not result in a decreased nocturnal melatonin secretion in mice.Target:50-Hz magnetic field.
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Riferimento:J Clin Pharm Ther. 2001 Aug;26(4):297-301.Azione della melatonina:The oncostatic action of melatonin warrants to eluci- date whether the induced increase of blood melato- nin concentration is essential to successful CMF (cyclophosphamide, methotrexate, 5-fluorouracil) chemotherapy.Target:Plasma melatonin concentration
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Riferimento:Cancer Causes Control. 2001 Apr;12(3):279-87. Review.Azione della melatonina:Electric lighting contributes to 'circadian disruption' may be an important cause of 'endocrine disruption' and contribute to a high risk of breast cancer.Target:LAN
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Riferimento:Carcinogenesis. 2001 Jul;22(7):1043-8.Azione della melatonina:MF may cause uncoupling of signal transduction from melatonin receptors to adenylyl cyclase.Target:Magnetic fields/cAMP
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Riferimento:Environ Health Perspect. 2001 May;109(5):501-7. Erratum in: Environ Health Perspect 2001 Jul;109(7):A304.Azione della melatonina:All-night exposure to magnetic fields had no effect on the blood levels of melatonin or estradiol. While nocturnal melatonin levels were suppressed in women exposed to LAN.Target:Magnetic fields (EMF) Light at night (LAN)
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Riferimento:Alcohol Alcohol. 2001 May-Jun;36(3):276-7.Azione della melatonina:Alcohol administration has been reported to reduce the nocturnal rise in serum melatonin in rats and in humans under experimental conditions.Target:Alcohol's effects
Anno: 2002
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Riferimento:J Pineal Res. 2002 Mar;32(2):90-6.Azione della melatonina:Melatonin (1nM) and dihydroxycholecalciferol (D3) (100 nM) reduce MCF-7 cell proliferation by modulating cell-cycle length through the control of the p53-p21 pathway.Target:D3/p53/p21
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Titolo: Modulation of intracellular calcium and calmodulin by melatonin in MCF-7 human breast cancer cellsRiferimento:J Pineal Res. 2002 Mar;32(2):112-9.Azione della melatonina:Melatonin (10(-7) M) effects on the Ca2+/CaM path-way play a role in the growth-inhibitory on MCF-7 human breast cancer cells.Target:(Ca2+)/calmodulin (CaM)