Melatonina
Anno: 2008
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Riferimento:Med Hypotheses. 2008 Dec;71(6):862-7.Azione della melatonina:Portion of the survival benefit of Aromatase inhibtors (AIs) is due to their indirect effect on melatonin, not just their direct effect on estrogen.Target:Aromatase inhibitors (AIs)
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Riferimento:J Pineal Res. 2008 Nov;45(4):341-50.Azione della melatonina:Highly protective of oxidative damage to the human hemopoietic system.Target:Disruption of nocturnal melatonin synthesis andrelated circadian rhythms by electric fields.
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Riferimento:Eur J Cancer Prev. 2008 Oct;17(5):467-72.Azione della melatonina:Positive relationship between the sleep variation and E2 levels (60% lower) in women of reproductive age.Target:17-beta estradiol (E2)
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Titolo: An indomethacin analogue...Riferimento:Biochem Pharmacol. 2008 Jan 15;75(2):484-93.Azione della melatonina:Identification of CBM as a specific inhibitor of AKR1C3 and the resultant effects on prostate and breast cancer cells.Target:N-(4-chlorobenzoyl)- melatonin (CBM)
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Riferimento:Curr Cancer Drug Targets. 2008 Dec;8(8):691-702.Azione della melatonina:Melatonin inhibits the growth of breast cancer by interacting with estrogen-signaling(SERM)-(SEEM) pathways.Target:Selective estrogen recetor modulator (SERM), selective estrogen enzyme modulator (SEEM).
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Titolo: Suppression of implanted MDA-MB 231 human breast cancer growth in nude mice by dietary walnutRiferimento:Nutr Cancer. 2008;60(5):666-74.Azione della melatonina:Tumor cell proliferation was decreased, but apoptosis was not altered due to walnut consumption.Target:Walnuts diet.
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Riferimento:Endokrynol Pol. 2008 May-Jun;59(3):200-6.Azione della melatonina:Not influenced the activity of GSH-Px, either in normal or in pinealectomised rats after ADR. A deficiency of endogenous melatonin production may inhibit GSH-Px activity.Target:ADR; GSH-Px.
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Titolo: Melatonin and estradiol effects on food intake, body weight, and leptin in ovariectomized ratsRiferimento:Maturitas. 2007 Sep 20;58(1):91-101.Azione della melatonina:In ovariectomized rats,melatonin reduced food intake and partially prevented the increase of body weight and cholesterol, without changing leptin levels.Target:Sulphatoxymelatonin (aMT6s).
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Riferimento:G Ital Med Lav Ergon. 2008 Jul-Sep;30(3):276-9.Azione della melatonina:Shift-work has been associated with breast cancer, due to a circadian disruption and to a nocturnal suppression in melatonin production.Target:Shift-work.
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Riferimento:J Pineal Res. 2008 Apr;44(3):307-15.Azione della melatonina:Melatonin administration (2 mg/kg BW/day) enhances survival under LD conditions, the results are self-defeating when they coexist with circadian disruption as under LL conditions.Target:Light-dark (LD) Continuous light (LL).