Melatonina
Anno: 2008
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Riferimento:Br J Cancer. 2008 Nov 4;99(9):1502-5.Azione della melatonina:In a prospective study on Japanese women, short sleep duration was associated with higher risk of breast cancer.Target:LAN
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Riferimento:Hybridoma (Larchmt). 2008 Jun;27(3):205-9.Azione della melatonina:Anti-melatonin monoclonal antibodies (Mab) may be useful for immunoassay of melatonin.Target:Mab-BSA( bovine serum albumin) intraperitonally.
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Riferimento:J Pineal Res. 2008 Apr;44(3):307-15.Azione della melatonina:Importance of taking into account endogenous rhythmicity and limiting melatonin administration to the subjective night (2 mg/kg BW/day) in order to restrict melanoma progression.Target:Circadian rhythmicity.
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Riferimento:Breast Cancer Res Treat. 2008 Apr;108(3):339-50.Azione della melatonina:Melatonin,at physiological concentration,suppresses estrogen receptor(ER) gene, modulates several estrogen dependent regulatory proteins and pro-oncogenes, inhibits cell proliferation, and impairs the metastatic capacity of MCF-7 human breast cancer cells.Target:Estrogen receptor (ER)
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Riferimento:In Vivo. 2008 May-Jun;22(3):397-400.Azione della melatonina:MLT with s.c. low-dose IL-2 caused a statistically significant reduction of the radiotherapy-induced effect.Target:Lymphocyte growth factor (IL-2).
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Riferimento:Cancer Lett. 2008 Sep 18;268(2):272-7.Azione della melatonina:Melatonin inhibition of telomerase activity supports a possible role in treatment of estrogen-dependent tumors.Target:HumanTelomerase ReverSeTranscriptase (hTERT)
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Riferimento:Aviat Space Environ Med. 2007 Apr;78(4 Suppl):A26-37.
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Riferimento:Integr Cancer Ther. 2008 Sep;7(3):189-203.Azione della melatonina:Melatonin's oncostatic actions include the direct augmentation of natural killer (NK) cell activity, which increases immunosurveillance, stimulation of cytokine production and protection on hematopoietic precursors from the toxic effect of anticancer chemotherapeutic drugs.Target:Immunomodulation, hematopoiesis, and antioxidative processes.
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Riferimento:Carcinogenesis. 2008 Jun;29(6):1244-8.Azione della melatonina:Melatonin inhibition of telomerase activity supports a possible role in treatment of estrogen-dependent tumors.Target:HumanTelomerase ReverseTranscriptase (hTERT)
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Riferimento:J Natl Cancer Inst. 2008 Jun 18;100(12):898-905.Azione della melatonina:Statistically significant inverse association between melatonin levels, as measured in overnight morning urine, and invasive breast cancer risk in postmeno pausal women.Target:6-sulfatoxymelatonin.