Letter: The pineal and neoplasia
Lancet. 1975 Jan 4;1(7897):34-5.
Buswell RS.
No Abstract
No Abstract
Leucemie Linfomi Mielomi
Leucemie Linfomi Mielomi
[Melatonin as a possible endogenous leukemogenic (blastomogenic) agent]
Gematol Transfuziol. 1983 Feb;28(2):47-50.
Romanenko VI.
No Abstract
No Abstract
The clinical significance of melatonin serum determination in oncological patients and its correlations with GH and PRL blood levels
Eur J Cancer Clin Oncol. 1987 Jul;23(7):949-57.
Lissoni P, Bastone A, Sala R, Mauri R, Rovelli F, Viviani S, Bajetta E, Esposti D, Esposti G, di Bella L, et al.
The oncological patients showed significantly higher mean melatonin serum levels than the control subjects. Mean melatonin values were lower in patients with solid tumours who had metastases, than in cases without metastases. GH and PRL serum levels were similar to control subjects.
MLT-GH-PRL.
Intracellular metabolism of biogenic amines in paraneurons
Arch Histol Cytol. 1989;52 Suppl:69-74.
Hasegawa H, Kobayashi T, Inoue F, Ichiyama A.
Serotonin is one of the representative biogenic amines produced from tryptophan in the gastrointestinal tract as well as in the brain. The capacity to synthesize serotonin depends on the existence of tryptophan monooxygenase. The activity of tryptophan monooxygenase in paraneurons such as mastocytomas and enterochromaffin cells depends on available ferrous iron.
L-5HTP monooxygenase.
Melatonin-induced suppression of human lymphocyte natural killer activity in vitro
J Pineal Res. 1989;7(2):153-64.
Lewiński A, Zelazowski P, Sewerynek E, Zerek-Mełeń G, Szkudliński M, Zelazowska E.
Melatonin-10(-6) M and 10(-10) M- resulted in an inhibition of NK activity.
Natural killer (NK)
Role of pineal melatonin and melatonin-induced-immuno-opioids in murine leukemogenesis
Med Oncol Tumor Pharmacother. 1992;9(2):87-92.
Conti A, Haran-Ghera N, Maestroni GJ.
Accelerated leukemogenesis whereas the surgical pinealectomy and the functional pinealectomy delayed it.
Daily melatonin 4 mg/kg b.w.
Breast cancer mortality among female electrical workers in the United States
J Natl Cancer Inst. 1994 Jun 15;86(12):921-5.
Loomis DP, Savitz DA, Ananth CV.
Exposure to extremely low-frequency electromagnetic fields reduces the pineal gland's nocturnal production of the hormone melatonin.
Electric or magnetic fields.
Melatonin concentrations in pineal organ culture are suppressed by sera from tumor-bearing mice
J Pineal Res. 1994 Aug;17(1):17-9.
Leone AM, Skene D.
Melatonin rhythmicity is suppressed in cancer patients.
Plasma borne tumor-associated factor (TAMF).
The nuclear receptor for melatonin represses 5-lipoxygenase gene expression in human B lymphocytes
J Biol Chem. 1995 Mar 31;270(13):7037-40.
Steinhilber D, Brungs M, Werz O, Wiesenberg I, Danielsson C, Kahlen JP, Nayeri S, Schräder M, Carlberg C.
Melatonin is a natural ligand of RZR alpha and RZR beta, down-regulating the expression of 5-lipoxygenase about 5-fold in B-Lymphocytes.
Retinoid Z receptor (RZR alpha and beta).
Physical inactivity of murine retrovirus infected C57BL/6 mice is prevented by melatonin and dehydroepiandrosterone
Proc Soc Exp Biol Med. 1998 Nov;219(2):144-8.
Araghi-Niknam M, Lane L, Watson RR.
DHEA or MLT supplementation restored the average speed; ambulatory time and distance traveled of retrovirus infected mice.
LP-BM5 retrovirus infection.
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