Explanation for the observed ornithine decarboxylase (ODC) changes after magnetic fields (MF) exposure is the melatonin hypothesis.

Research on a melatonin-inhibited carcinogenesis in the low-risk populations of the Arctic should be pursued.

The inclusion of morning urine widespread testing of the role played by melatonin in human health and disease.

EMF and light at night, might contribute to mammary carcinogenesis through inhibition of melatonin.

Effect of MLT in combination with IL-2 or other cytokines in cancer patients and viral diseases including HIV-infected patients.

The small number of clinical studies focusing on the possible therapeutic value of melatonin (1nM) on breast cancer is surprising.

Melatonin may act as an antioxidant that can scavenge free radicals and protect against DNA damage.

Melatonin (1nM) actions support a possible usefulness in the prevention and treatment of mammary gland malignancy.

Essential participation of endogenous opioids in hormonal regulation, a response to stress caused by beginning chemotherapy.

The growth-inhibitory effects of melatonin are transduced through the membrane-associated G-protein coupled mt1 melatonin receptor.