Diminished pineal function coincides with disturbed circadian endocrine rhythmicity in untreated primary cancer patients. Consequence of premature aging or of tumor growth?

Ann N Y Acad Sci. 1994 May 31;719:502-25. Review.
Bartsch C, Bartsch H, Flüchter SH, Mecke D, Lippert TH.
No abstract available.
No abstract available.

Differences between pulsatile or continuous exposure to melatonin on MCF-7 human breast cancer cell proliferation

Cancer Lett. 1994 Sep 30;85(1):105-9.
Cos S, Sánchez-Barceló EJ.
Antiproliferative effect was obtained by sequential exposure to 10(-9) M/10(-11)M 12/12h melatonin, which mimics the physiological rhythm of serum melatonin concentration.
Physiological rhythm/serum melatonin concentration

Serial transplants of 7,12-dimethylbenz[a]anthracene-induced mammary tumors in Fischer rats as model system for human breast cancer. 3. Quantitative ultrastructural studies of the pinealocytes and plasma melatonin concentrations in rats bearing an advance

Biol Signals. 1994 Nov-Dec;3(6):302-6.
Karasek M, Marek K, Zielinska A, Swietoslawski J, Bartsch H, Bartsch C.
Plasma melatonin concentrations in tumor-bearing rats killed at 3.00 h were suppressed by 35% when compared to the control animals killed at the same time.
Plasma melatonin concentrations


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